Effect of furacin on the dissimilation of pyruvate and formate by cell-free extracts of bacteria.

Previously it has been shown that Furacin (5-nitro-2-furaldehyde semicarbazone) inhibited the dismutation of pyruvate by whole resting cells of Micrococcus pyogenes var. aureus (1). Other earlier studies have also shown that both pyruvate dismutation and the formation of acetylmethylcarbinol (AMC) by cell-free extracts of pigeon breast muscle were markedly inhibited by Furacin (2). We are reporting here further investigation by us of the effects of Furacin on dissimilation of pyruvate and formate by cell-free extracts of bacteria.